ELISA Substrates and Reagents
Cayman Chemical 11keto TStosTRon ELISA n
A DGAT1 inhibitor (IC50 57 nM) selective for DGAT1 over DGAT2 ACAT-1 and ACAT-2 (IC50s >10000 nM for all) inhibits HCV replication in HCV-infected Huh7.5 cells at 50 UM. inhibits palmitic acid-induced apoptosis and increases in triglyceride levels in MIN6 cells decreases serum triglyceride levels in an oral lipid tolerance test in dogs at 1 mg/kg
Cayman Chemical p38a MAPK-IN-1 5mg
A p38α MAPK inhibitor (IC50 = 5,500 nM in an HTRF assay); inhibits LPS-induced TNF-α production in THP-1 cells (EC50 = 6,200 nM); has been used in the study of p38α MAPK inhibitor binding interactions and kinetics
Bioss Ikb- Ser-32/Ser-36 Phosphos
I B (Ser-32/Ser-36) Primary Antibody Unconjugated Host Species Mouse Target Species Human Mouse Rat Clonality Monoclonal Applications WB IP 39A1413Concentration Size 100 ul Storage Buffer PBS 0 5% BSA and 0 05% NaN3
ABclonal Technology Phospho-α-Synuclein-S129 Rabbit pAb
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimers disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene.
Surmodics Inc TMB Super Slow One Component HRP Microwell Substrate, 1L
The BioFX™ one component 3,3’,5,5’-tetramethylbenzidine (TMB) substrate is supplied in a ready-to-use solution. Peroxidase reacts with the TMB substrate solution to produce a soluble blue reaction product that can be read at 370 nm or 620-650 nm for ELISA applications. Stop solutions can be added to prevent further color development and reading the absorbance values at the desired wavelengths.
ABclonal Technology Phospho-PPP1R12A-S507 Rabbit pAb
Myosin phosphatase target subunit 1 (MBS) is a key component of myosin phosphatase, which regulates actin-myosin interactions downstream of the Rho GTPase. RhoA, when active in its GTP-bound form, interacts with MBS to control myosin light chain (MLC) phosphorylation, influencing smooth muscle contraction and nonmuscle cell movement. Rho-kinase, activated by GTP-bound RhoA, phosphorylates and inactivates MBS, reducing myosin phosphatase activity. Overexpression of RhoA or activated RhoA increases MLC phosphorylation. Several transcript variants encoding different isoforms of this gene have been identified.
ABclonal Technology Phospho-HSP27/HSPB1-S82 Rabbit pAb
This gene encodes a member of the small heat shock protein (HSP20) family of proteins. In response to environmental stress, the encoded protein translocates from the cytoplasm to the nucleus and functions as a molecular chaperone that promotes the correct folding of other proteins. This protein plays an important role in the differentiation of a wide variety of cell types. Expression of this gene is correlated with poor clinical outcome in multiple human cancers, and the encoded protein may promote cancer cell proliferation and metastasis, while protecting cancer cells from apoptosis. Mutations in this gene have been identified in human patients with Charcot-Marie-Tooth disease and distal hereditary motor neuropathy.
Meso Scale Discovery R-PLEX Human HSP27/HspB1 ASYQP
The R-PLEX Human HSP27 (HSPB1) Assay is an ELISA kit for the quantitative measurement of HSP27 in human serum plasma cell culture supernatants cell and tissue lysates and other biological fluids It uses a quantitative sandwich immunoassay technique and comes with a 96-well strip plate that is pre-coated with antibodies specific for HSP27 The detection range for this assay is 15 6-1000 pg/mL with a sensitivity of 5 pg/mL This assay kit provides materials to run up to 40 samples in duplicate and takes around 3 hours to complete Overall the R-PLEX Human HSP27 Assay provides a sensitive high-throughput method for quantifying HSP27 levels in various human sample types
Meso Scale Discovery RPLEX HUM ERK1/2 total ASYQP
The R-PLEX Human ERK1/2 Total Assay Kit from Meso Scale Discovery is used to quantitatively measure total ERK1/2 levels in cell lysates The assay uses an electrochemiluminescent detection method and provides high sensitivity broad dynamic range and requires low sample input The kit includes a 96-well plate coated with capture antibody detection antibody read buffer wash buffer blocker solutions calibrator and positive control lysate The assay can detect total ERK1/2 levels between 50 pg/mL to 50 000 pg/mL It is compatible with lysates from adherent and suspension cultured cells The kit provides all necessary reagents for the immunoassay
Zymo Research Corporation 5-mC Coating Buffer, 15 ml
5-mC Coating Buffer for use in the 5-mC DNA ELISA kit for DNA methylation quantification. Sold individually or as part of a complete ELISA kit.